Skip to main content
. 2022 Nov 9;13:980231. doi: 10.3389/fimmu.2022.980231
COVID-19 coronavirus disease 2019
RNAse R ribonuclease R
SARS-CoV-2 severe acute respiratory syndrome coronavirus 2
CoVs coronaviruses
PKR Protein Kinase R
RNase L ribonuclease L
NF90 nuclear factor 90
NF110 nuclear factor 110
Calu-3 human lung adenocarcinoma cells
SARS-CoV-1 severe acute respiratory syndrome coronavirus 1
MERS-CoV middle east respiratory syndrome coronavirus
ORF open reading frame
nsps nonstructural proteins
S spike
E envelope
M membrane
N nucleocapsid
ACE2 angiotensin-converting enzyme 2
DPP4 dipeptidyl peptidase 4
TMPRSS2 transmembrane serine protease 2
CatB cathepsin B
CatL cathepsin L
AAK1 AP2-associated kinase 1
TLRs toll-like receptors
TF transcription factor
SIRs systemic inflammatory responses
IL-6 interleukin-6
ncRNAs non-coding RNAs
hpi hours post-infection
ecircRNA exonic circRNA
ciRNA intronic circRNA
EIciRNA exon-intronic circRNA
ceRNA competing endogenouse RNA
miRNA microRNA
lncRNA long noncoding RNA
mRNA messenger RNA
HFL-I human embryonic lung fibroblast cell
ILF3 human interleukin-enhanced binding factor 3
dsRNA double-stranded RNA
CircRNPs circRNA-protein complexes
RIG-I retinoic acid inducible gene-I
HIF-1 hypoxia-inducible factor-1
mTOR mammalian leukemia target of pamycin
TNF tumor necrosis factor
MAPK mitogen-activated protein kinase
ISG interferon-stimulated gene
IFN interferon
OAS1-3 2'-5' oligoadenylate synthase
Ifit1-3 interferon-inducible protein
Th1 T helper cell type 1
2'-5'A 2'-5' oligoadenylate
PKR Protein Kinase R
RA arthritic
HUVSMCs human vascular smooth muscle cells
HUVECs human vascular endothelial cells
RLRs RIG-I-like receptors
FSJs forward splicing junctions
SRY sex-determining region Y
AXL AXL receptor tyrosine kinase
RTK receptor tyrosine kinase
NF-kB nuclear factor-kB
NOS2 inducible nitric oxide synthase
PLpro papain-like protease
ERK extracellular signal-regulated kinase
RBD receptor-binding domain