TABLE 2.
Subgroup analysis of tumor classification.
| Outcome | Subgroup | Study number | Sample size | RR (95%CI) | p-value | Heterogeneity | |
|---|---|---|---|---|---|---|---|
| I2 (%) | p-value | ||||||
| Disease recurrence | Overall | 9 | 6445 | 0.85 (0.74–0.96) | 0.01 | 42 | 0.09 |
| Tumor classification | |||||||
| Solid cancer | 6 | 5156 | 0.88 (0.78–0.99) | 0.04 | 31 | 0.2 | |
| Hematology malignancy | 3 | 1289 | 0.70 (0.48–1.02) | 0.06 | 55 | 0.11 | |
| Clinical response | Overall | 13 | 2640 | 1.24 (1.03–1.49) | 0.02 | 63 | 0.001 |
| Tumor classification | |||||||
| Solid cancer | 8 | 1146 | 1.56 (1.03–2.36) | 0.04 | 75 | 0.0002 | |
| Hematology malignancy | 5 | 1494 | 1.09 (0.98–1.21) | 0.11 | 0 | 0.87 | |
| Overall survival | Overall | 14 | 9521 | 0.98 (0.95–1.01) | 0.23 | 18 | 0.26 |
| Tumor classification | |||||||
| Solid cancer | 12 | 9139 | 0.98 (0.95–1.02) | 0.3 | 23 | 0.22 | |
| Hematology malignancy | 2 | 382 | 1.02 (0.42–2.47) | 0.96 | 15 | 0.28 | |