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. 2022 Nov 9;13:1065320. doi: 10.3389/fgene.2022.1065320

TABLE 2.

Subgroup analysis of tumor classification.

Outcome Subgroup Study number Sample size RR (95%CI) p-value Heterogeneity
I2 (%) p-value
Disease recurrence Overall 9 6445 0.85 (0.74–0.96) 0.01 42 0.09
Tumor classification
 Solid cancer 6 5156 0.88 (0.78–0.99) 0.04 31 0.2
 Hematology malignancy 3 1289 0.70 (0.48–1.02) 0.06 55 0.11
Clinical response Overall 13 2640 1.24 (1.03–1.49) 0.02 63 0.001
Tumor classification
 Solid cancer 8 1146 1.56 (1.03–2.36) 0.04 75 0.0002
 Hematology malignancy 5 1494 1.09 (0.98–1.21) 0.11 0 0.87
Overall survival Overall 14 9521 0.98 (0.95–1.01) 0.23 18 0.26
Tumor classification
 Solid cancer 12 9139 0.98 (0.95–1.02) 0.3 23 0.22
 Hematology malignancy 2 382 1.02 (0.42–2.47) 0.96 15 0.28