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. 2022 Nov 9;12:1022879. doi: 10.3389/fcimb.2022.1022879

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Copyright © 2022 Pan, Wei, Yuan, Kong, Yang, Zhang, Cui, Chen, Liu and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pediococcus pentosaceus treatment improved the methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced oxidative stress and regulated the levels of Keap1 and Nrf2. (A) Representative western blotting images of SOD1 and GPx1. (B) Quantitative analysis of SOD1. (C) Quantitative analysis of GPx1. (D) Representative western blotting images of Keap1 and Nrf2. (E) Quantitative analysis of Keap1. (F) Quantitative analysis of Nrf2. β-actin was used as internal reference. Statistical comparison by one-way ANOVA with post-hoc comparisons of Dunnett’s multiple-comparisons test. Data are presented as means ± SEM; n = 4–6 per group. ^* P < 0.05 vs. Con group, ^** P < 0.01 vs. Con group, ^# P < 0.05 vs. MPTP group, ^## P < 0.01 vs. MPTP group.