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. 2022 Nov 9;12:1022879. doi: 10.3389/fcimb.2022.1022879

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Copyright © 2022 Pan, Wei, Yuan, Kong, Yang, Zhang, Cui, Chen, Liu and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pediococcus pentosaceus treatment reversed the methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced abnormal microbiota composition. (A) Shannon index of gut microbial diversity. (B) Simpson index of gut microbial diversity. (C) Principal coordinate analysis plots of gut microbial diversity. (D) Venn diagram and quantitative analysis of microbial community composition among three groups. (E) Relative abundance of gut microbiota at the family level among three groups. (F) Relative abundance of gut microbiota at the genus level among three groups. Statistical comparison by Kruskal–Wallis rank sum test with post-hoc comparisons of Tukey–Kramer. Data are presented as median + interquartile range. ^** P < 0.01 vs. Con group, ^## P < 0.01 vs. MPTP group.