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. 2022 Nov 9;10:1036380. doi: 10.3389/fchem.2022.1036380

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Copyright © 2022 Liu, Zhao, Liu, Huang and Xia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BYHWD decreased the fat accumulation in the liver and reduced the serum lipid levels: (A) representative HE images from four groups; (B) HE scores’ comparison; (C) CHOL, TG, and LDL comparison among the four groups; (D) the comparison of FFAs in the liver and in the serum among the four groups; (E) representative images of liver tissue section staining by Oil Red O; (F) the comparison of the Oil Red O ratio among the four groups. Data are shown as means ± S.D (n = 6–8). Statistical analysis was performed by one-way ANOVA, followed by Tukey’s multiple comparisons test for the false discovery rate. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001 were set to compare the mean of each group with the mean of every other group.