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. 2022 Nov 9;10:1036380. doi: 10.3389/fchem.2022.1036380

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Copyright © 2022 Liu, Zhao, Liu, Huang and Xia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Influences of BYHWD on gut microbiota in diabetic ZDF rats: (A) Venn analysis; (B) alpha-indexes of Chao1, Shannon, Simpson, and Good’s coverage comparison among the four groups; (C) observed OTUs; (D) the histogram of the top 10 phyla of the relative abundance of the intestinal flora; (E) the histogram of the top 10 genera of the relative abundance of the intestinal flora. Data are shown as means ± S.D (n = 6–8). Statistical analysis was performed using one-way ANOVA, followed by Tukey’s multiple comparisons test for the false discovery rate. *p < 0.05 and **p < 0.01 were set to compare the mean of each group with the mean of the DM group.