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. 2022 Nov 9;10:1036380. doi: 10.3389/fchem.2022.1036380

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Copyright © 2022 Liu, Zhao, Liu, Huang and Xia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BYHWD affected the lipid metabolism displayed by multivariate statistical analysis: (A) PCA plots of the four study groups; (B) PLS-DA plots of the four groups; (C) permutations plots of the four study groups; (D) OPLS-DA plots of the four study groups; (E) OPLS-DA plots of DM, DM + BYHWD, and DM + DMBG groups; (F) OPLS-DA plots of the DM and DM + BYHWD groups. The red circle represents the rat’s sample from the control group; the deep-blue square represents the rats’ samples from the DM group; the light-blue diamond represents the rats’ samples from the DM + BYHWD group, and the orange triangle represents the rats’ samples from the DM + DMBG group.