Table 9.

The binding free energy (kcal/mol) of the vaccine and receptor complex.

Energy components	Binding free energies (kcal/mol)
	Vaccine–MHC-I	Vaccine–MHC-II	Vaccine–TLR3	Vaccine–TLR4
Van der waals	−157.07	−229.96	−138.50	−197.16
Electrostatic energy	−3,064.98	−6,116.41	−2,898.84	−6,857.22
Solvation term	3,234.28	6,347.10	3,012.70	7,072.07
Non-polar solvation	−21.00	−32.06	−18.45	−27.04
Total energy	−8.65	−31.36	−43.10	−9.19