Table 1.
New mutations of CARD9 over the past 4 years.
| Mutation | Identified year | Patient age | Patient sex | Country | Fungus | Organ involvement | References |
|---|---|---|---|---|---|---|---|
| p.V261fs | 2018 | 8 | F | Turkey | Prototheca zopfii | Digestive tract/mucous membrane | Sari et al., 2018 |
| p.Gln295Ter | 2018 | 17 | F | Turkey | Candida albicans | Oral/respiratory tract/CNS | Cetinkaya et al., 2018 |
| c.1269+18G>A | 2019 | 31 | M | NA | Trichophyton rubrum/Trichophyton violaceum/Aspergillus fumigatus/Aspergillus flavus | Skin/Nail/Lymph nodes | Nazarian et al., 2020 |
| Ala586Gly | 2019 | 30 | F | China | Trichophyton rubrum | Skin/nails | Huang et al., 2019 |
| c.692C>T | 2019 | 46 | F | China | Mucor irregularis | Skin | Wang et al., 2019 |
| c.905_907delTCT | 2019 | 46 | F | China | Mucor irregularis | Skin | Wang et al., 2019 |
| c.586A>G (p.K196E) | 2021 | 4 | F | Japan | Exophiala dermatitidis | Lymph nodes/CNS | Imanaka et al., 2021 |
| c.610C>T (R204C) | 2021 | Child | M | China | Talaromyces marneffei | Skin/lung/liver/lymph nodes/spleen | Ba et al., 2021 |
| Q370X (c.1108C>T) | 2021 | 26 | F | India | Exserohilum rostratum | Skin | Kalantri et al., 2021 |
| c.A586G | 2021 | 6 | M | China | Alternaria species | CNS | Lai et al., 2021 |
F, female; M, male; CNS, central nervous system.