Table 2.
Sources of lncRNAs in the RIG-I signaling pathway.
| LncRNA name | Sources of lncRNAs | Reference |
|---|---|---|
| LncRNAs regulate RIG-I negatively or positively | ||
| Lnc-Lsm3b | Macrophages, multiple types of immune cells and organs | (Jiang et al. 2018) |
| LncATV | Monocytes, erythroleukemia cells and hepatoma cell | (Fan et al., 2019) |
| LncRNA GAS5 | SMC and aortic tissue of AAA mice | (Le et al., 2021) |
| LncRNA NEAT1 | T lymphocytic cell lines Jurkat, MT4 and THP-1 cells | (Ma et al. 2017) |
| LncRNA functions as a ceRNA to target MAVS in the RIG-I signaling pathway | ||
| LncRNA MARL | Miiuy croaker chromosome 14 | (Chu et al., 2020) |
| LncRNAs affect TRIM25-mediated ubiquitination in the RIG-I signaling pathway | ||
| LncNSPL | IAV-infected THP-1 human monocytes | (Jiang et al., 2022) |
| LncRNA AVAN | PBMC, CD14’monocytes, derived macrophages, and BEAS-2B | (Lai et al. 2021) |
| Lnc-Lsm3b | Macrophages, multiple types of immune cells and organs | (Jiang et al. 2018) |
| Lnc-zc3 h7a | HEK 293T cells and RAW264.7 cells | (Lin et al. 2019) |
| LncRNAs participate in phosphorylation-mediated regulation of the RIG-I signaling pathway | ||
| LncRNA-GM | Monocytes, macrophages and other immune cells, including CD4+T cells, CD8+T cells, γδT cells, NK cells, neutrophils, and eosinophils | (Wang et al., 2020) |
| LncRNA MaIL1 | Macrophages and monocytes | (Aznaourova et al., 2020) |
| LncLrrc55-As | The antisense transcripts of the Lrrc55 gene | (Zhou et al., 2019) |
| LncATV | Monocytes, erythroleukemia cells and hepatoma cell | (Fan et al., 2019) |
| LncRNA AFAP1-AS1 | Various tumor tissues and NSCLC cells lines | (Tang et al. 2018) |
| LncRNA RDUR | The cytoplasm and nucleus of A549cells | (Chen et al. 2021) |
| LncRNA TCONS-00058367 | Physical contiguity PML | (Ma et al. 2019) |
| LncRNAs regulate the expression of ISGs via the RIG-I signaling pathway | ||
| Lnc-MxA | Be an ISG in the nucleus in IAV-infected cells | (Li et al. 2019) |
| LncRNA ISR | A549 and HEK293T cells | (Pan et al. 2019) |
| Lnc-ISG20 | A549 and HEK293T cells | (Chai et al. 2018) |
| Lnc-ISG15 | HuH7 and A549 cells | (Barriocanal et al., 2014) |
| LncBST2/BISPR | HuH7 and A549 cells | (Barriocanal et al., 2014) |
| LncRNA-155 | A549 cells | (Maarouf et al. 2019) |
| LncRNA NRAV | Chromosome 12q24.31 in A549 and 293T cell lines | (Ouyang et al. 2014) |
| LncRNA CMPK2/NRIR/EGOT | Human hepatocytes | (Carnero et al. 2016) |
| LncRNA-IFI6 | JFH1-infected Huh7.5.1 cells and PHHs | (Liu et al., 2018) |
| LncRHOXF1 | Human X chromosome | (Penkala et al. 2016) |
| The triangle relationship between lncRNAs, RIG-I signaling pathway, and glycolysis | ||
| LncRNA IGFBP4–1 | Human lung adenocarcinoma cancer cell lines (A549, PC-9, and GLC-82) | (Yang et al., 2017) |
| LncRNA TUG1 | Hepatocellular carcinoma cell | (Lin et al., 2018) |
| LncRNA PVT1 | GBC tissue | (Chen et al., 2019) |
| LncRNA DLRU2 | HEC-1, HEC-50, HHUA, Ishikawa, KLE cells, and endometrial epithelial cell line | (Dong et al., 2021) |
| LncRNA HISLA | Macrophages | (Chen et al., 2019) |
| LncRNAs regulate the RIG-I signaling pathway in COVID-19 infection | ||
| LncRNA EGOT | BALF | (Yang et al., 2021) |
| LncRNA MALAT1 | BAL cells | |
| LncRNA NEAT1 | NHBE cells, BAL cells | |
| LncRNA WAKMAR2 | BALF | |
| LncRNA DANCR | Inflammation-prone lung tissues | |
| LncRNA NONHSAT122723.2 | PBMC | |
| LncRNA Gm26917 | Unknown | |
| LncRNA TUG1 | Hepatocellular carcinoma cell | (Lin et al., 2018) |
| LncRNAs exhibit antitumor immunity through the regulation of the RIG-I signaling pathway | ||
| LncRNA AFAP1-AS1 | Various tumor tissues and NSCLC cells lines | (Tang et al. 2018) |
| LncRNA FTX | The cis-acting regulatory region of the imprinted XCI | (Liu et al., 2018) |
The table summarizes the sources of different lncRNAs and references to the source articles. SMC, smooth muscle cells; AAA, Abdominal aortic aneurysm; PBMC, peripheral blood mononuclear cells; A549, human lung epithelial cells; HEK293T, human embryonic kidney cells; PML, promyelocytic leukemia; BEAS-2B, a human normal lung epithelial cell; GBC, Gallbladder cancer; NSCLC cell lines: A549, H1975, H1650, H1395, and H1299; PHHS, Primary Human Hepatocytes; Lrrc55, leucine rich repeat containing 55; BALF, bronchoalveolar lavage fluid; NHBE, normal human bronchial epithelial; XCI, X-chromosome inactivation.