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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Biomed Pharmacother. 2022 Oct 28;156:113939. doi: 10.1016/j.biopha.2022.113939

Fig. 7.

Fig. 7.

Changes in non-eupneic breathing index (NEBI) and NEBI/frequency of breathing (NEBI/Freq). Panels A and C: NEBI and NEBI/Freq values during various stages of the experiment, respectively. Panels B and D: Sum of NEBI and NEBI/Freq responses recorded during infusion of vehicle (VEH; 20 μL/min, IV) or L-CYSee (INF; 14.3 μmol/kg/min, IV), upon injection of morphine (MOR, 10 mg/kg, IV) and following injection of VEH (100 μL/100 g body weight, IV) or L-CYSee (250 μmol/kg, IV), respectively. Data are presented as mean ± SEM. There were 5 rats in the vehicle-infusion group and 6 rats in the L-CYSee-infusion group.*P < 0.05, significant change from Pre values. †P < 0.05, L-CYSee versus VEH.