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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Biomed Pharmacother. 2022 Oct 28;156:113939. doi: 10.1016/j.biopha.2022.113939

Fig. 9.

Fig. 9.

Actual values for Alveolar-arterial (A-a) gradient prior to (Pre) following an injection of morphine (M5–M60; 10 mg/kg, IV) in freely-moving rats receiving a continuous infusion (I30-I90) of vehicle (VEH; 10 μL/min), L-serine ethyl ester (L-SERee, 7.15 μmol/kg/min, IV) or L-cysteine ethyl ester (L-CYSee, 7.15 μmol/kg/min, IV). The data are presented as mean ± SEM. There were 8 rats in the vehicle-infusion group and 6 rats in the L-SERee-infusion and L-CYSee-infusion group.* P < 0.05, significant change from Pre values. † P < 0.05, L-CYSee versus VEH.