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. 2022 Nov 9;10:1003505. doi: 10.3389/fpubh.2022.1003505

Table 4.

Genotype distribution in five genetic models in females.

Genotype Genetic model NAFLD (N) Non-NAFLD (N) OR 95% CI p FDR p1 FDR1
rs12409877 Codominant 0.089 0.111 0.034* 0.043*
A/A 254 111 1.00
A/G 30 25 1.91 1.07 3.39
G/G 3 2 1.53 0.25 9.26
Dominant 0.029* 0.069 0.011* 0.028*
A/A 254 111 1.00
A/G-G/G 33 27 1.87 1.07 3.26
Overdominant 0.031* 0.069 0.010* 0.028*
A/A-G/G 257 113 1.00
A/G 30 25 1.90 1.07 3.37
log-Additive 0.041* 0.069 0.021* 0.036*
0,1,2 287 138 1.68 1.03 2.76
rs10770141 Codominant 0.022* 0.056 0.217 0.281
G/G 255 111 1.00
A/G 33 24 1.67 0.94 2.96
A/A 0 2 0
Dominant 0.040* 0.067 0.225 0.281
G/G 255 111 1.00
A/G-A/A 33 26 1.81 1.03 3.17
log-Additive 0.022* 0.056 0.167 0.281
0,1,2 288 137 1.89 1.11 3.22
rs2292354 Overdominant 0.049* 0.229 0.047* 0.202
G/G-A/A 218 89 1.00
G/A 81 51 1.54 1.00 2.37

CI, confidence interval; FDR, false discovery rate; NAFLD, non-alcoholic fatty liver disease; OR, odds ratio; SNPs, single nucleotide polymorphisms.

p1 and FDR1 indicate p value and adjusted p value by FDR method after adjusting age and BMI.

* and **

indicate p < 0.05 and p < 0.01, respectively.