TABLE 1.
Baseline demographics of patients.
| Shenfu injection group (n = 1128) | Control group (n = 1183) | p-Value | |
|---|---|---|---|
| Age, y | 71 [60, 81] | 70.0 [59, 80] | 0.18 |
| Men, No. (%) | 682 (60.50) | 743 (62.80) | 0.26 |
| BMI, kg/m2 | 27 [25, 29] | 26 [24, 29] | 0.60 |
| SOFA at enrollment | 9 [6, 11] | 9 [6, 10] | 0.78 |
| Source of infection, No. (%) | |||
| Lung | 479 (42.46) | 496 (41.93) | 0.82 |
| Abdominal | 246 (21.81) | 223 (18.85) | 0.09 |
| Urogenital | 109 (9.66) | 125 (10.57) | 0.52 |
| Systolic blood pressure (mmHg) | 78.73 [65.13, 96.48] | 76.21 [67.11, 94.38] | 0.69 |
| Central venous pressure (mmHg) | 8.30 [6.50, 11.20] | 9.40 [6.50, 12.90] | 0.42 |
| Heart rate (beats/min) | 116.20 [81.20, 139.30] | 122.40 [88.20, 144.60] | 0.32 |
| Lactates (mmol/L) | 5.35 [1.12, 10.98] | 5.12 [1.58, 11.54] | 0.19 |
| PaO2/FiO2 | 178.30 [111.20, 321.20] | 182.10 [124.30, 367.30] | 0.88 |
| ALT, U/L | 11.18 [0.13, 26.80] | 13.06 [0.34, 26.33] | 0.99 |
| Creatinine, μmol/L | 73.22 [11.19, 116.50] | 69.21 [8.92, 106.92] | 0.12 |
| eGFR, ml/min • 1.73m2 | 69.08 [33.47, 91.98] | 66.48 [38.33, 95.66] | 0.42 |
| PT, s | 15.51 [12.13, 16.24] | 15.34 [12.05, 17.45] | 0.19 |
| TBIL, μmol/L | 20.41 [6.47, 36.61] | 20.69 [6.57, 37.09] | 0.89 |
| Comorbidities, No. (%) | |||
| Diabetes | 234 (20.74) | 259 (21.89) | 0.53 |
| Hypertension | 463 (41.04) | 516 (43.62) | 0.23 |
| Coronary disease | 198 (17.55) | 212 (17.92) | 0.86 |
| Chronic kidney disease | 102 (9.04) | 94 (7.94) | 0.38 |
| COPD | 321 (28.45) | 309 (26.12) | 0.23 |