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. 2022 Nov 9;13:1041326. doi: 10.3389/fphar.2022.1041326

TABLE 2.

Effects of SFI in septic shock patients receiving MV in different models.

Variable Crude model Model 1 Model 2
HR (95%CI) p-value HR (95%CI) p-value HR (95%CI) p-value
28-day mortality 0.766 (0.628–0.933) 0.008 0.752 (0.617–0.917) 0.005 0.749 (0.613–0.914) 0.004
vasopressor therapy 0.705 (0.641–0.776) p < 0.001 0.701 (0.637–0.771) p < 0.001 0.704 (0.639–0.775) p < 0.001
length of ICU stay 0.734 (0.668–0.808) p < 0.001 0.729 (0.663–0.802) p < 0.001 0.732 (0.665–0.806) p < 0.001
time to extubation 0.692 (0.630–0.761) p < 0.001 0.687 (0.625–0.756) p < 0.001 0.687 (0.625–0.756) p < 0.001
organ failure 0.814 (0.745–0.889) p < 0.001 0.807 (0.738–0.882) p < 0.001 0.819 (0.749–0.896) p < 0.001

Model 1: adjusted for sex and age.

Model 2: adjusted for sex, age, body mass index, heart rate, blood creatinine, glomerular filtration rate, brain natriuretic peptide, cardiac troponin, creatine kinase isoenzymes, procalcitonin, total bilirubin and prothrombin time.