Table 2.

Model parameters that vary by disease state.

Diagnosis	C brain †	C csf ‡	C plasma †	B brain	B csf	B plasma	F *
Units	pg/g	pg/ml	pg/ml	pg	pg	pg
Control	5.92*107	337	2.58	7.70*1010	1.01*105	9.03*103	0.092
MCI	8.71*107	339	2.71	1.13*1011	1.02*105	9.49*103	0.094
AD	8.74*107	403	3.12	1.14*1011	1.21*105	1.09*104	0.088

^†Level of tau in the brain was expressed as pg of tau per g of brain tissue.

^‡These values should be considered representative as opposed to authoritative.

Brain and CSF levels from Han et al. (2017). Plasma levels based on ADNI cohort (Mattsson et al., 2016). More recent studies show higher values for both CSF and plasma tau (Barthélemy et al., 2020).

^*F was calculated using (12).