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. Author manuscript; available in PMC: 2023 Jan 5.
Published in final edited form as: Biochemistry. 2022 Jun 24;61(13):1260–1272. doi: 10.1021/acs.biochem.2c00157

Figure 6.

Figure 6.

(A) Bromodomain phylogenetic tree adapted from Pomerantz et al..37 BDs tested in the PrOF NMR screen are highlighted. (B) Table showing PrOF NMR Kd values from the titration of 40 bp dsDNA with 5FW-labeled proteins. N.B. = binding affinity could not be determined. a: Kd is reported as the mean ± SD of two experimental replicates. b: Kd is reported as the mean ± SD of three experimental replicates.