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The evolution of (a) pressure waveforms of RV and PA, and (b) RV pressure-volume loop over 1000-day period. From day 0 (baseline) to 250, the PA and RV pressures are elevated and RVEDV does not alter significantly. From day 250 to 1000 with drop in RV contractility and increase in TBV, RVPSP, RVEDP and RVEDV increases that mimic the decompensated phase of PAH.
