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. 2022 Nov 23;19(196):20220534. doi: 10.1098/rsif.2022.0534

Table 1.

The model parameters of the PA, the RV and the closed-loop system at s = 0.

PA geometry RPA(s=0) (mm)a 11.3
LPA(s=0) (mm)a 64.0
HPA(s=0) (mm)a 1.02
mass M(s=0) (kg mm−2)a,b 1.07 × 10−6
collagen mass fraction ϕc(s=0)c 0.35
mass turnover kqκ=14 (day−1)b 0.02
mbκ=12=mκ=12(s=0) (kg mm−2 day−1)a,b 7.51 × 10−10
mbκ=34=mκ=34(s=0) (kg mm−2 day−1)a,b 3.00 × 10−9
deposition stretch Ghκ=14c 1.08
mechanical properties k1 (N mm kg−1)c 2.29 × 105
k2 3.62
reference stress σhκ=1=σκ=1(s=0) (MPa)c 0.0183
σhκ=2=σκ=2(s=0) (MPa)c 0.0318
σhκ=34=σκ=34(s=0) (MPa)c 0.0269
SMC mass fraction ϕm(s=0)c 0.25
mass turnover kqκ=14 (1/day)b 0.02
mbm=mm(s=0) (kg mm−2 day−1)a,b 5.37 × 10−9
deposition stretch Ghmc 1.06
mechanical properties m1 (N mm kg−1)c 5.47 × 104
m2c 3.63
reference stress σhm (MPa)c 0.0203
elastin mass fraction ϕe(s=0)c 0.4
deposition stretch Gh,11e=Gh,22ec 1.15
mechanical properties c (N mm kg−1)c 7.06 × 104
RV geometry RRV(s=0) (mm)a 36.0
HRV(s=0) (mm)a 8.10
passive properties C(s=0) (MPa)b 0.7 × 10−3
bfb 20.0
active properties Tmax(s=0) (MPa)b 0.145
Ca0=(Ca0)max (µM)b 4.35
lr (µm)b 1.85
l0 (µm)b 1.58
B (µm−1)b 1.43
t0 (ms)b 270
ttr (ms)b 405
τr (ms)b 25
circulatory system Rpv=Rpa (MPa ms−1 ml−1)d 0.002
Rcp(s=0) (MPa ms−1 ml−1)d 0.05
Rcv (MPa ms−1 ml−1)d 0.004
Ccp(s=0) (ml MPa−1)d 6.5 × 103
Ccv (ml MPa−1)d 3.5 × 103
Vcp,r (ml)d 2.0
Vcv,r (ml)d 10.0

aPatient-specific acquired by the MR images.

bGeneral estimation by the previous studies [9, 20, 27].

cPatient-specific by optimization in the previous study [13].

dCalibration to fit the patient-specific clinical P–V relationship of PA and RV.