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. 2022 Mar 1;13(2):225–235. doi: 10.32598/bcn.12.6.2062.1

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Copyright© 2022 Iranian Neuroscience Society

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Figure 3. — Effect of minocycline on the amplitude of field excitatory postsynaptic potentials (fEPSP) recorded from the dentate gyrus area of rat hippocampus

In the treatment protocol (A and B), control (normal saline) and minocycline were injected intraperitoneally (IP) once daily for 7 days after reperfusion, while in the pretreatment protocol (C and D), single doses of control and minocycline were given IP to rats 60 min prior to ischemic injury. Each symbol indicates the Mean±SEM (n=6) (field excitatory postsynaptic potentials).

^*P<0.05, ^**P<0.01, and ^***P<0.001 (all compared with baseline); #P<0.05, ##P<0.01, and ###P<0.001 (all compared to the control group at the relevant time).