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. 2022 Mar 1;13(2):225–235. doi: 10.32598/bcn.12.6.2062.1

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Copyright© 2022 Iranian Neuroscience Society

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Figure 4. — Effect of Minocycline on the Activity of Antioxidant Enzymes in the Hippocampus

In the treatment protocol (A–C), control (normal saline) and minocycline were injected intraperitoneally (IP) once daily for 7 days starting after reperfusion, while in pretreatment protocol (D–F), a single dose of control or minocycline was administered IP to rats 60 min before the ischemia. Each column indicates the Mean±SEM (n=6).

++P<0.01, +++P<0.001 (both compared to the sham group); ^**P<0.01 ^***P<0.001 (both compared to the control group).

GPx: glutathione peroxidase; SOD: superoxide dismutase.