Table-5.

In vivo intra-renal iron uptake in different groups (μg/dL).

Groups/Parameters	Untreated control	Cis	Cis + Infliximab	Cis + MSCs	Cis + Infliximab-labeled PEG-coated SPIONs-loaded MSCs	p-value
Serum iron after 20 min from injection	39.05 ± 1.88	37.48 ± 1.51	41.21 ± 2.77	44.15 ± 2.33	128.55* ± 3.12	0.03121
Serum iron after 40 min from injection	39.17 ± 1.63	40.23 ± 3.52	38.25 ± 3.19	45.20 ± 4.81	83.36* ± 2.17	0.03500
Kidney iron after 40 min from injection	74.22 ± 3.26	66.09 ± 4.54	72.27 ± 4.91	66.73 ± 5.59	112.23* ± 3.51	0.02111

In the same row, *is significantly different at p < 0.05. Cis=Cisplatin; MSC=Mesenchymal stem cells; PEG=Polyethylene glycol; SPIONS=Superparamagnetic iron oxide nanoparticles