Table 1. Demographic Data of the Clinical Groups in the DDI Study and Trønderbrain Cohorts.
| Characteristic | Patients, No. (%) | |||
|---|---|---|---|---|
| Control group | AD group | AD-MCI group | AD-dementia group | |
| DDI study cohort | ||||
| No. | 63 | 77 | 72 | 5 |
| Age, median (range), y | 62 (41-77) | 68 (46-80)a | 68 (46-80)a | 73 (58-75) |
| Sex | ||||
| Male | 27 (42.9) | 47 (61.0)a | 44 (61.1)a | 3 (60.0) |
| Female | 36 (57.1) | 30 (39.0)a | 28 (38.9)a | 2 (40.0) |
| APOE4 allele | 25 (39.7) | 56 (72.7)a | 53 (73.6)a | 3 (60.0) |
| MMSE score, median (range) | 30 (27-30) | 27 (18-30)a | 27 (21-30)a | 25 (18-28)a |
| Trønderbrain cohort | ||||
| No. | 54 | 49 | 30 | 19 |
| Age, median (range), y | 68 (57-84) | 64 (54-72)a | 64 (54-72)a | 64 (54-69)a |
| Sex | ||||
| Male | 18 (33.3) | 24 (49.0) | 15 (50.0) | 9 (47.4) |
| Female | 36 (66.7) | 25 (51.0) | 15 (50.0) | 10 (52.6) |
| APOE4 allele | 20 (37.0) | 42 (85.7) | 24 (80.0)a | 18 (94.7)a |
| MMSE score, median (range) | 30 (28-30) | 26 (16-30)a | 28 (23-30)a | 24 (16-27)a,b |
Abbreviations: AD, Alzheimer disease; AD-MCI, AD with mild cognitive impairment; DDI, Dementia Disease Initiation; MMSE, Mini-Mental State Examination.
a
P < .01 compared with control group.
b
P < .01 compared with AD-MCI group.