TABLE 2.
Frequency of thrombotic blood vesselsa
| C. perfringens strain | Total no. of blood vessels | No. (%) of vessels with thrombosis |
|---|---|---|
| Wild-type heat-killed (JIR325)c | 201 | 0 |
| Wild-type (JIR325)b | 478 | 68 (14.2) |
| Theta-toxin-deficient (JIR4081)b | 485 | 63 (13.0) |
| Alpha-toxin deficient (JIR4120)c | 466 | 2 (0.4) |
a
Analysis of the frequency of thrombotic blood vessels in tissue samples taken 8 to 12 h postinjection. Thrombosis was determined by the presence of pale pink occlusions within hematoxylin and eosin-stained vessels, like those indicated in Fig. 1E and G, correlating to areas of platelet and fibrin deposition.
b
Differs significantly from tissues injected with heat-killed C. perfringens cells (P < 0.0001).
c
Differs significantly from tissues injected with wild-type C. perfringens cells (P < 0.0001).