Table 1.
Association of high Siglec-15 expression with the clinicopathological characteristics of 91 patients with retroperitoneal liposarcoma
| Characteristics | Total | High Siglec-15 expression (%) | Low Siglec-15 expression (%) | P value |
|---|---|---|---|---|
| Gender | ||||
| Male | 52 | 31(59.6) | 21(40.4) | 0.582 |
| Female | 39 | 21(53.8) | 18(46.2) | |
| Age | ||||
| ≤60 | 55 | 30(54.5) | 25(45.5) | 0.536 |
| >60 | 36 | 22(61.1) | 14(38.9) | |
| Tumor size | ||||
| ≤15 | 16 | 11(68.8) | 5(31.2) | 0.301 |
| 15-30 | 50 | 25(50.0) | 25(40.0) | |
| >30 | 25 | 16(64.0) | 9(36.0) | |
| FNCLCC Grade | ||||
| Low (G1) | 20 | 12(60.0) | 8(40.0) | 0.770 |
| High (G2, G3) | 71 | 40(56.3) | 31(43.7) | |
| Histology | ||||
| DDLPS | 61 | 34(55.7) | 27(44.3) | 0.682 |
| WDLPS | 21 | 14(66.7) | 7(33.3) | |
| PLPS | 7 | 3(42.9) | 4(57.1) | |
| MLPS | 2 | 1(50.0) | 1(50.0) | |
| Multifocality | ||||
| No | 54 | 30(55.6) | 24(44.4) | 0.830 |
| Yes | 37 | 22(59.5) | 15(40.5) | |
| Recurrence | ||||
| No | 38 | 27(56.3) | 21(43.7) | 0.856 |
| Yes | 43 | 25(58.1) | 18(41.9) | |
| Necrosis | ||||
| No | 60 | 39(65.0) | 21(35.0) | 0.035 |
| Yes | 31 | 13(41.9) | 18(58.1) |
Abbreviations: SD, standard deviation; FNCLCC, Federation Nationale des Centres de Lutte Contre le Cancer; Siglec-15, sialic acid-binding immunoglobulin-like lectin-15; WDLPS, well-differentiated liposarcoma; DDLPS, dedifferentiated liposarcoma; PLPS, pleomorphic liposarcoma; MLPS, myxoid/round cell liposarcoma.