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. 2022 Oct 17;18(16):6035–6051. doi: 10.7150/ijbs.76573

Figure 5.

Figure 5

Downregulation of SEPT5 altered the population and composition of immune cells. The population of immune cells was detected via CyTOF, (A) A representative images of the cell subsets in living cells and in CD45-positive cells; (B) The proportion of cell subsets in living cells was counted (n = 4); (C) The proportion of cell subsets in CD45-positive cells was counted (n = 4); The expression of CD8a and GZMA was detected by IHC, (D) A representative image and statistical results for CD8a; (E) A representative image and statistical results for GZMA; (F) The correlation between SEPT5 expression and CD8+ T cell infiltration in PCa patients; Data are depicted as the mean ± SEM. * P < 0.05, ** P < 0.01 and *** P < 0.001, determined by one-way ANOVA.