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. 2022 Oct 17;18(16):6035–6051. doi: 10.7150/ijbs.76573

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Downregulation of SEPT5 activated cytokine-related signaling pathways. RNA-seq was performed in RM1 cells with SEPT5 knockdown and corresponding control cells. (A) The 1444 upregulated and 164 downregulated DEGs are presented; (B) Top 20 DEGs identified by DO enrichment analysis; (C) Top 20 DEGs identified by GO enrichment analysis; (D) Top 20 DEGs identified by DO KEGG analysis; (E) Top 20 DEGs identified by Reactome enrichment analysis; (F) Heatmap showed the expression of cytokine-related genes; (G) Heatmap showed the expression of chemokine-related genes.