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. Author manuscript; available in PMC: 2022 Nov 23.
Published in final edited form as: Bioconjug Chem. 2020 Jul 20;31(8):1960–1970. doi: 10.1021/acs.bioconjchem.0c00324

Scheme 1.

Scheme 1.

iFab Was Produced by Papain Digestion of the Clinical Product, Remicadea

aSubsequent conjugation of iFab to CHP was achieved by a two-step, lysine-based conjugation via a sulfo-SMCC heterobifunctional linker.