Table 2.

Mean core diameter ${}^a$ , hydrodynamic diameter and Zeta potential ${}^b$ of gold nanospheres in the absence and presence of alendronate, memantine, and tobramycin

Gold nanospheres	Core D. ± SD (nm)	Hydrodynamic D. ± SD (nm)	Zeta potential ± SD (mV)
AuNSs	9.58 ± 1.27	52.08 ± 3.54	− 24.56 ± 1.33
AuNSs with Alen (micro)	9.34 ± 1.07	58.94 ± 7.3	− 30.23 ± 3.61${}^c$
AuNSs with Mema (nano)	–	64.99 ± 2.32	0.26 ± 0.25
AuNSs with Mema (micro)	9.59 ± 0.87	98.41 ± 1.05	0.53 ± 0.63
AuNSs with Tobr (nano)	10.01 ± 0.95	135.3 ± 4.75	− 23.63 ± 0.75
AuNSs with Tobr (micro)	9.90 ± 1.05	332.16 ± 38.54	− 1.64 ± 1.24

${}^a$ The average core diameter was calculated from multiple HRTEM images

${}^b$ The average hydrodynamic diameter and average Zeta Potential were calculated from three DLS metrics

${}^c$ Unstable nanospheres, Zeta potential outside the range (− 30– +30 mV) are not stable