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. 2022 Nov 22;13:68. doi: 10.1186/s13293-022-00477-5

Fig. 1.

Fig. 1

Workflow and analysis design. We retrieved relevant studies from GEO-NCBI and ArrayExpress data repositories and performed differential expression analysis on each selected study after data exploration and preprocessing. We performed a comparison for each brain region and an additional comparison for all samples and performed a gene meta-analysis for each comparison. Finally, we applied several functional profiling methodologies to characterize the results of the SN meta-analysis