Table 1.
Comparison of demographic, clinical and ultrasound parameters between parathyroid carcinoma/atypical parathyroid tumor and parathyroid adenoma
| parathyroid carcinoma/atypical parathyroid tumor (n = 16) |
parathyroid adenoma (n = 20) | p-value | |
|---|---|---|---|
| Mean age (years) | 46.9 ± 12.7 | 52.9 ± 13.1 | 0.178 |
| Gender (male/female) | 6/10 | 8/12 | 0.878 |
| Median PTH (pg/ml) | 1384.4(441–1881) | 241.3(108–529) | < 0.001 |
| Median Ca (mMol/L) | 3.39(2.96–3.61) | 2.91(2.89–3.57) | 0.005 |
| Median P (mMol/L) | 0.61(0.50–0.78) | 0.82(0.50–0.94) | 0.017 |
| Median ALP (IU/L) | 225.5(157–281) | 107.5(90–136) | 0.003 |
| Symptoms | < 0.001 | ||
| 0 | 1 (6.3%) | 12 (60%) | |
| 1 | 9 (56.2%) | 8 (40%) | |
| 2 | 6 (37.5%) | 0 (0%) | |
| Size (cm) | 3.07 ± 1.32 | 2.85 ± 1.16 | 0.600 |
| DR* | 2.11 ± 0.60 | 2.71 ± 0.81 | 0.018 |
| Location | 0.053 | ||
| Right | 9 (56.3%) | 9 (45%) | |
| Left | 7 (43.7%) | 11 (55%) | |
| Shape | < 0.001 | ||
| Oval/round | 1 (6.3%) | 16 (80.0%) | |
| Irregular | 15 (93.7%) | 4 (20.0%) | |
| Echogenicity | 0.009 | ||
| Homogeneous | 1 (6.3%) | 10 (50%) | |
| Heterogeneous | 15 (93.7%) | 10 (50%) | |
| Calcification | 3 (18.8%) | 0 (0%) | 0.078 |
| Cystic change | 9 (56.3%) | 11 (55%) | 0.650 |
| Infiltration | 13 (81.3%) | 6 (30.0%) | 0.002 |
DR*: the ratio between the maximum size and the minimum size of parathyroid lesions in longitudinal and transverse dimensions