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. 2022 Nov 6;4(6):fcac286. doi: 10.1093/braincomms/fcac286

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© The Author(s) 2022. Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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P-tau 217, 231, 202/205/208 (AT8) and 202/205 (AH36) colocalize, but p-tau 181 does not. Representative images of cortices from frozen coronal brain sections immunostained with antibodies against (A) p-tau 217 and p-tau 202/205/208 (AT8), (B) p-tau 231 and p-tau 202/205 (AH36), (C) p-tau 217 and p-tau 231 and (D, E) p-tau 181 and p-tau 217. Aβ plaques are detected by staining with FSB. Scale bars, 20 µm. Higher magnification views of the dashed orange squares are shown on the right side. White arrows show colocalization. Scale bars, 2.5 μm.