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. 2022 Sep 14;11(18):e025627. doi: 10.1161/JAHA.122.025627

Figure 2. Adjusted hazard ratio (aHR) for outcomes by IL‐6 quintile, stratified by race.

Figure 2

Adjusted for sex, age, and population stratification. aHRs with 95% CIs. The numbers 5, 4, 3, and 2 refer to the IL‐6 quintile. Quintile 1 is the reference group. A, The aHR per 1‐quintile increase in IL‐6 for death in White and Black participants, respectively, were 1.53 (1.42–1.64) vs 1.29 (1.20–1.38) (P<0.001 for interaction). B, The aHR for CVD composite for White and Black participants, respectively, were 1.61 (1.50–1.74) vs 1.30 (1.22–1.39) (P<0.001 for interaction). C, The aHR for progression of CKD for White and Black participants, respectively, were 1.38 (1.28–1.48) vs 1.23 (1/16–1.31) (P=0.02 for interaction). D, The aHR for hemoglobin decline were, respectively, 1.37 (1/28–1.46), and 1.18 (1.12–1.24), (P<0.001 for interaction). BL indicates Black patients; CKD, chronic kidney disease; CVD, cardiovascular disease; HGB, hemoglobin; IL‐6, interleukin‐6; and WH, White patients.