Table 4.

Sensitivity and Specificity Parameters for Incident VTE by Different suPAR and D‐Dimer Centiles

Marker	Cutoff	Centile	Sensitivity (95% CI)	Specificity (95% CI)	Positive predictive value (95% CI)	Negative predictive value (95% CI)
suPAR, ng/mL	4.12	20	0.95 (0.91–0.98)	0.21 (0.19–0.23)	0.10 (0.09–0.10)	0.98 (0.96–0.99)
	4.54	25	0.91 (0.87–0.96)	0.26 (0.24–0.28)	0.10 (0.10–0.11)	0.97 (0.96–0.98)
	6.70	50	0.70 (0.63–0.77)	0.52 (0.50–0.54)	0.12 (0.11–0.13)	0.95 (0.94–0.96)
	10.1	75	0.47 (0.40–0.55)	0.75 (0.75–0.79)	0.16 (0.13–0.18)	0.94 (0.93–0.95)
D‐dimer, mg/L	0.50	20	0.95 (0.92–0.98)	0.21 (0.20–0.24)	0.12 (0.11–0.12)	0.97 (0.96–0.99)
	0.56	25	0.92 (0.88–0.96)	0.26 (0.25–0.29)	0.12 (0.12–0.13)	0.97 (0.95–0.98)
	1.03	50	0.78 (0.72–0.83)	0.53 (0.50–0.56)	0.15 (0.14–0.16)	0.96 (0.94–0.97)
	2.40	75	0.48 (0.41–0.55)	0.77 (0.75–0.79)	0.19 (0.16–0.21)	0.93 (0.92–0.94)

suPAR indicates soluble urokinase plasminogen activator receptor; and VTE, venous thromboembolism.