Table 1.
Characteristics of the Study Samples
| FHS | CARDIA, N=2300 | ||
|---|---|---|---|
| Characteristic | Derivation, N=451 | Validation, N=914 | |
| Age, y | 53±8 | 54±8 | 32±4 |
| Women, n (%) | 282 (63) | 444 (49) | 1021 (44) |
| White race, n (%) | 444 (98) | 904 (99) | 1277 (56) |
| Body mass index, kg/m2 | 27.3±5.5 | 27.9±5.2 | 25.7±5.0 |
| Systolic blood pressure, mm Hg | 118±14 | 119±14 | 108±11 |
| Total cholesterol, mg/dL | 188±33 | 192±34 | 176±33 |
| HDL cholesterol, mg/dL | 62±19 | 61±20 | 54±14 |
| Prevalent CVD, n (%) | 15 (3) | 38 (4) | 0 (0) |
| Diabetes, n (%) | 27 (6) | 59 (7) | 46 (2) |
| Smoking, n (%)* | 166 (37) | 336 (37) | 903 (39) |
| Peak VO2, mL/kg per min | 23.4±6.9 | 23.7±7.3 | … |
| Treadmill duration, min* | … | … | 9.9±2.6 |
| Cardiovascular health score* | … | … | 10.2±1.8 |
| CARDIA physical activity score, exercise units | … | … | 375±282 |
Displayed values are mean±SD for continuous variables and n (%) for categorical variables. CARDIA variables are at year 7. CARDIA indicates Coronary Artery Risk Development in Young Adults; CVD, cardiovascular disease; FHS, Framingham Heart Study; HDL, high‐density lipoprotein; and VO2, oxygen uptake.
*
Cardiovascular health score is available in 2205 individuals. Smoking is reported as current/former smoking. Treadmill duration reported at year 7 in CARDIA in participants achieving 85% maximal predicted heart rate (N=1985/2102 with available tests and metabolites).