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. 2022 Sep 14;11(18):e026399. doi: 10.1161/JAHA.122.026399

Table 2.

CMR Imaging Results Stratified by the Specific 2018 Lake Louis II Diagnosis of Myocarditis: Cardiac 18F‐FDG‐PET/CT Evidence of Myocardial Inflammatory Cell Infiltration

Patients Myocarditis (CMR) No myocarditis (CMR) Inflammatory cell infiltration (cardiac PET) No inflammatory cell infiltration (cardiac PET)
No. 26* 9 16 7 16
LV ejection fraction, % 61 [57–67] 59 [56–62] 64 [59–68] 62 [60–63] 60 [56–69]
LV EDVi, mL/m2 65 [62–72] 65 [60–73] 66 [62–72] 64 [56–75] 66 [62–72]
LV ESVi, mL/m2 25 [21–29] 25 [21–32] 22 [21–27] 2 [20–32] 26 [21–30]
LV SVi, mL/m2 42 [34–48] 38 [30–44] 44 [38–49] 38 [31–42] 44 [36–50]
RV ejection fraction, % 56 [48–60] 50 [47–58] 58 [54–60] 52 [48–56] 59 [52–61]
T1–maximum, ms 1356 [1304–1412] 1342 [1301–1403] 1372 [1322–1414] 1317 [1297–1405] 1380 [1335–1424]
T2–maximum, ms 62 [57–68] 68 [67–70] 58 [56–62] 66 [64–69] 60 [56–63]
ECV, maximum % 31 [28–34] 34 [31–36] 29 [27–32] 33 [31–35] 30 [27–34]
LGE, % 9 (35) 6 (67) 2 (12) 6 (86) 3 (19)
Subendocardial LGE, % 2 (8) 2 (22) 0 (0) 2 (29) 0 (0)
Mid‐wall, % 8 (31) 5 (56) 2 (12) 5 (71) 3 (19)
Myocarditis‐specific Lake Louis criteria, CMR 9 (36) 5 (71) 3 (20)
Myocardial inflammatory cell infiltration, PET 7 (30) 5 (63) 2 (14)
Pulmonary inflammation, percentage of lung 17 [3–29] 16 [2–30] 17 [10–31] 7 [2–20] 22 [13–38]
Pulmonary consolidation, percentage of lung 12 [7–18] 10 [8–16] 13 [7–18] 9 [8–12] 16 [7–19]

Data are provided as number, number (percentage), or median [interquartile range]. 18F‐FDG indicates 2‐deoxy‐2‐[fluorine‐18]fluoro‐D‐glucose; CMR, cardiac magnetic resonance; CT, computed tomography; ECV, extracellular volume; EDVi, indexed end‐diastolic volume; ESVi, indexed end‐systolic volume; LGE, late gadolinium enhancement; LV, left ventricle; PET, positron emission tomography; RV, right ventricle; SVi, systolic volume indexed; T1, longitudinal relaxation time; and T2, horizontal relaxation time.

*

Denominators differ for each modality because not all scans were performed/diagnostic on every patient.