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. 2022 Nov 23;11:e77285. doi: 10.7554/eLife.77285

Table 2. Top 10 novel protein-coding genes significant by colocalization (RCP ≥0.5) and TWAS, sorted by TWAS p value.

Gene Tissue with greatest RCP Max. RCP TWAS p value (Bonferroni) # GTEx tissues with RCP ≥0.5
SPTBN1 Cells_Cultured_fibroblasts 0.9469 <5 × 10−324 2
PPP6R3 Thyroid 0.5291 5.7 × 10−93 1
BARX1 Colon_Transverse 0.7764 6.36 × 10−63 1
MEOX2 Brain_Nucleus_accumbens_basal_ganglia 0.6286 3.21 × 10−53 3
RERE Adipose_Subcutaneous 0.6431 6.95 × 10−46 4
SIPA1 Nerve_Tibial 0.9981 4.26 × 10−41 1
CAPZB Testis 0.6716 3.64 × 10−33 1
B4GALNT3 Artery_Aorta 0.9241 2.67 × 10−33 4
TRPC4AP Breast_Mammary_Tissue 0.5577 8.62 × 10−31 3
AXL Minor_Salivary_Gland 0.6205 9.74 × 10−31 3