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. 2022 Sep 26;11:e66697. doi: 10.7554/eLife.66697

Appendix 3—figure 7. The distribution of the 3rd central moment at equilibrium.

Appendix 3—figure 7.

We show the positive/negative contribution to the 3rd central moment per unit mutational input (A) (based on Equation A3-34) and per segregating variant (B), as a function of effect size squared. The contributions become substantial for large effect sizes, i.e., when S=a24 .