Table 2. Genotype and allele frequencies of Rho-kinase1 gene rs35996865 and Rho-kinase2 gene rs2230774 (Thr431Asn) polymorphisms among cases and controls.
| Genotypes/alleles | Patients with AA (n=93)n (%) | Controls (n=93) n (%) | p | |
|---|---|---|---|---|
| ROCK1 rs35996865 | ||||
| T/T | 56 (60.2) | 55 (59.1) | ||
| T/G | 35 (37.6) | 33 (35.5) | 0.8946 | |
| G/G | 2 (2.2) | 5 (5.4) | 0.4392 | |
| T | 147 (79.0) | 143 (76.9) | ||
| G | 39 (21.0) | 43 (23.1) | 0.7075 | |
| ROCK2 rs2230774 (Thr431Asn) | ||||
| G/G | 30 (32.3) | 25 (26.9) | ||
| G/T | 44 (47.3) | 52 (55.9) | 0.3890 | |
| T/T | 19 (20.4) | 16 (17.2) | 0.9808 | |
| G | 104 (55.9) | 102 (54.8) | ||
| T | 82 (44.1) | 84 (45.2) | 0.9169 | |
AA: acute appendicitis; ROCK: Rho-kinase.