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. 2022 Sep 6;2022:6897056. doi: 10.1155/2022/6897056

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Copyright © 2022 Songsong Pan et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Immunofluorescence imaging of PGP9.5 and Ku80 in the sciatic nerve. (a) PGP9.5 was highly expressed in the PMSC group but lower in the control group at 7, 14, and 28 days. Contrarily, the upregulation of PGP9.5 by PMSCs was significantly inhibited by LGK974, and there was statistically significant difference at 14 days. The results demonstrated that KU80 was expressed in sciatic nerve. (b) Quantitative measurements were expressed as mean fluorescence intensity. Data were mean ± SEM. n = 3; ^∗PMSC group vs. control group, P<0.05; ^#PMSC group vs. PMSC+LGK974 group, P < 0.05. The scale bar: 50 μm.