Figure 1.

The shift in oral microbiota composition at the phylum and species levels

A. Composition of oral microbiota at the phylum level in each sample. P1–P6, six periodontitis specimens; C1–C3, three control specimens. For both periodontitis and control samples, every five samples were pooled together as one specimen. B. Comparison of relative aboundance of each phylum between periodontitis and control samples. The significantly abundant phyla in periodontitis samples are marked with red. The three small boxplots in the boxplot-in-boxplot indicate a zooming state for their corresponding boxplots in a vertical direction in the main boxplot. C. Eight species with significant differences in relative aboundance between periodontitis and control samples. The significantly abundant species in periodontitis and control samples are marked in red and light blue, respectivley. D. LEfSe analysis at the phylum level. E. LEfSe analysis at the species level. LDA, linear discriminant analysis; LEfSe, linear discriminant analysis effect size.