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. 2022 Nov 23;9:720. doi: 10.1038/s41597-022-01822-4

Table 2.

Summary of included data sorted according to ASC induction methods.

Induction Method Articles Datasets Number of Applications Mean sample size per dataset ± SD
Pharmacological 2C-B (4-Bromo-2,5-Dimethoxyphenethylamine) 2 2 51 25.5 ± 13.4
4-FA (4-Fluoroamphetamine) 1 3 36 12
5-MeO-DMT (5-Methoxy-N,N- Dimethyltryptamine) 5 15 932 62.1 ± 79.7
DMT + MAO* Inhibitor (“Ayahuasca”) 11 20 436 21.8 ± 18.3
DMT (N,N-Dimethyltryptamine) 9 22 295 13.4 ± 8
DXM (Dextromethorphan) 1 7 84 12
D-Amphetamine 1 8 32 4
D-Methamphetamine 1 1 8 8
Ergotamine 1 3 51 17
Ibogaine 1 1 27 27
Kambô (Giant Leaf Frog) 1 4 22 22
Ketamine 24 33 599 18.1 ± 7.3
LSD (Lysergic Acid Diethylamide) 20 66 2494 37.8 ± 151.6
Mazindol 1 1 10 10
MDA (3,4-Methylene dioxy amphetamine) 1 3 36 12
MDE (3,4-Methylenedioxyethylamphetamine) 2 2 22 11 ± 4.2
MDMA (3,4-Methylenedioxy methamphetamine, “Ecstasy”) 20 45 815 18.1 ± 9
Mescaline (Peyote, San Pedro cacti) 1 1 12 12
Psilocybin (“Magic Mushrooms”) 35 112 1900 17 ± 12.2
Salvinorin-A (Salvia Divinorum) 10 69 692 8.2 ± 10
THC (Tetrahydrocannabinol) 1 1 19 19
Triazolam 2 4 64 16 ± 4.6
Non-pharmacological Chanting (religious) 1 9 401 44.6 ± 27
Drumming and Dancing 2 3 187 62.3 ± 38.9
Flicker Light Stimulation 1 6 144 24
Ganzfeld 3 13 306 23.5 ± 5.2
Hetero-Hypnosis 8 20 1059 53 ± 78.7
Kundalini Meditation 1 1 12 12
Mind Machine 1 2 60 30
Olfactory Epithelium Stimulus 1 1 12 12
Sweat Lodge 1 2 110 55
Zen Meditation 1 1 14 14

This table contains, the sum of journal articles reporting on each of the identified induction method (“Articles”), the sum of experiments conducted (“Datasets”), the sum of all applications of the questionnaires on individual study participants (“Applications”), as well as the sample size per dataset given as mean ± standard deviation (“Mean sample size per dataset ± SD”).

*MAO: Monoamine oxidase Olfactory Epithelium Stimulus is not an induction method itself, but it is investigated as the mechanism underlying breathing techniques.