Figure 3.

Correlation between differentially abundant gut microbes and age

A.–E. Alluvial plots illustrating age-dependent phylogenetic shifts of the top 10 differentially abundant taxa at the phylum (A), class (B), order (C), family (D), and genus (E) levels. Differentially abundant taxa are ranked by their median of abundance. F. and G. Heatmaps showing significant age correlations for differentially abundant phyla (F) and genera (G) with FDR < 0.05. P values are calculated by the Spearman correlation test. For genera, only the top 40 genera ranked by |r| are shown. FDR, false discovery rate.