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. 2021 Dec 30;20(2):350–365. doi: 10.1016/j.gpb.2021.09.009

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© 2021 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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The interactive networks of gut microbiota

The interactive networks of gut microbiota in the infant (A), young-adult (B), middle-aged (C), and elderly (D) groups, as well as in all fecal samples (E), are constructed from the SparCC results, and visualized using Cytoscape. Genera with average abundance > 0.1%, correlation |r| > 0.2, and P < 0.05 are included in the networks. Node color denotes the phylum of a certain genus. Node size represents the weighted node connectivity. Edge color and thickness represent correlation r. SparCC, sparse compositional correlation.