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. 2022 Nov 10;13:1054504. doi: 10.3389/fmicb.2022.1054504

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Copyright © 2022 Zhao, Cui, Wu, Ren, Zhu, Xie, Zhang, Yang, Peng, Lai, Huang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of hypoxia on the structure of colon microbiota in normal mice and antibiotic drinking mice. (A) Intestinal microbial community diversity in each group (Shannon). Meaning: Wilcoxon. (B) Gut microbiome richness (observed species) in colonic luminal samples of each group. Significance: Wilcoxon. (C) Principal Coordinate Analysis (PCoA) of Unweighted UniFrac Distance between groups. (D) Relative abundance at phylum level in each group (%). (E) Relative abundance at each family level (%). (F) Bipartite networks of indicator species analysis. It displays different treatment-specific ASVs in the colonic bacterial communities using indicator species analysis. Circles represent individual bacteria and ASVs that are positively and significantly associated (p < 0.05) with one or more different grouping factors (association(s) given by connecting lines). ASVs are colored according to their Family assignment.