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. 2022 Nov 22;12:20142. doi: 10.1038/s41598-022-24465-2

Table 2.

Odds ratios for incident cataract surgery estimated with the categorical alcohol use patterns (both men and women).

Controls, N (%) Cases, N (%) OR (95% CI)
Model 1b Model 2c
Drinking frequency
Never 6953 (46.8) 6590 (44.3) 1 (reference) 1 (reference)
Former 1296 (8.7) 1227 (8.3) 1.07 (0.98–1.18) 1.00 (0.91–1.09)
1–3 days/week 3636 (24.5) 3657 (24.6) 1.13 (1.06–1.21) 1.10 (1.03–1.17)
4–7 days/week 2976 (20.0) 3387 (22.8) 1.32 (1.22–1.42) 1.30 (1.21–1.40)
P for trenda < 0.01 < 0.01
Average drinks
Never 6953 (46.8) 6590 (44.3) 1 (reference) 1 (reference)
> 0–2 drink/day 5641 (38.0) 5790 (39.0) 1.16 (1.09–1.23) 1.13 (1.06–1.20)
> 2–4 drink/day 1538 (10.3) 1698 (11.4) 1.27 (1.16–1.39) 1.23 (1.12–1.35)
> 4 drink/day 729 (4.9) 783 (5.3) 1.24 (1.10–1.39) 1.16 (1.03–1.31)
P for trenda < 0.01 < 0.01
Total amount of lifetime drinking
Never 6953 (46.8) 6590 (44.3) 1 (reference) 1 (reference)
> 0–40 drink–years 1307 (8.8) 1187 (8.0) 1.00 (0.91–1.10) 1.01 (0.92–1.10)
> 40–60 drink–years 1048 (7.1) 1093 (7.4) 1.18 (1.07–1.30) 1.16 (1.05–1.28)
> 60–90 drink–years 2602 (17.5) 2670 (18.0) 1.18 (1.09–1.27) 1.13 (1.05–1.22)
> 90 drink–years 2951 (19.9) 3321 (22.3) 1.32 (1.23–1.43) 1.25 (1.16–1.34)
P for trenda < 0.01 < 0.01

OR odds ratio, CI confidence interval.

aTrend test was calculated for the associations between alcohol use patterns as a continuous variable and incident cataract surgery.

bConditional logistic regression matched for sex, age, admission date, and hospital.

cAdditionally adjusted for smoking history, lifestyle-related comorbidities (hypertension, hyperlipidaemia, diabetes, and obesity), occupational radiation exposure, and outdoor work.