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. 2022 Nov 22;12:20142. doi: 10.1038/s41598-022-24465-2

Table 3.

Odds ratios for incident cataract surgery estimated with the categorical alcohol use patterns (men).

Controls, N (%) Cases, N (%) OR (95% CI)
Model 1b Model 2c
Drinking frequency
Never 1948 (26.4) 1948 (26.4) 1 (reference) 1 (reference)
Former 857 (11.6) 857 (11.6) 1.17 (1.03–1.33) 1.05 (0.93–1.19)
1–3 days/week 2056 (27.9) 2056 (27.9) 1.06 (0.95–1.18) 1.01 (0.91–1.12)
4–7 days/week 2506 (34) 2506 (34) 1.32 (1.20–1.47) 1.31 (1.19–1.45)
P for trenda < 0.01 < 0.01
Average drinks
Never 1948 (26.4) 1948 (26.4) 1 (reference) 1 (reference)
> 0–2 drink/day 3448 (46.8) 3448 (46.8) 1.13 (1.03–1.25) 1.09 (0.99–1.20)
> 2–4 drink/day 1333 (18.1) 1333 (18.1) 1.34 (1.20–1.50) 1.29 (1.16–1.45)
> 4 drink/day 638 (8.7) 638 (8.7) 1.29 (1.12–1.48) 1.21 (1.05–1.39)
P for trenda < 0.01 < 0.01
Total amount of lifetime drinking
Never 1948 (26.4) 1948 (26.4) 1 (reference) 1 (reference)
> 0–40 drink–years 543 (7.4) 543 (7.4) 0.93 (0.80–1.09) 0.92 (0.79–1.07)
> 40–60 drink–years 607 (8.2) 607 (8.2) 1.08 (0.93–1.25) 1.07 (0.93–1.24)
> 60–90 drink–years 1736 (23.6) 1736 (23.6) 1.15 (1.03–1.29) 1.11 (0.99–1.23)
> 90 drink–years 2533 (34.4) 2533 (34.4) 1.32 (1.20–1.47) 1.26 (1.14–1.39)
P for trenda < 0.01 < 0.01

OR odds ratio, CI confidence interval.

aTrend test was calculated for the associations between alcohol use patterns as a continuous variable and incident cataract surgery.

bConditional logistic regression matched for sex, age, admission date, and hospital.

cAdditionally adjusted for smoking history, lifestyle-related comorbidities (hypertension, hyperlipidaemia, diabetes, and obesity), occupational radiation exposure, and outdoor work.