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. 2022 Nov 22;12:20142. doi: 10.1038/s41598-022-24465-2

Table 4.

Odds ratios for incident cataract surgery estimated with the categorical alcohol use patterns (women).

Controls, N (%) Cases, N (%) OR (95% CI)
Model 1b Model 2c
Drinking frequency
Never 5005 (66.8) 4807 (64.1) 1 (reference) 1 (reference)
Former 439 (5.9) 365 (4.9) 0.89 (0.76–1.03) 0.91 (0.78–1.06)
1–3 days/week 1580 (21.1) 1784 (23.8) 1.22 (1.12–1.33) 1.23 (1.12–1.34)
4–7 days/week 470 (6.3) 538 (7.2) 1.23 (1.07–1.41) 1.34 (1.17–1.54)
P for trenda < 0.01 < 0.01
Average drinks
Never 5005 (66.8) 4807 (64.1) 1 (reference) 1 (reference)
> 0–2 drink/day 2193 (29.3) 2440 (32.6) 1.20 (1.11–1.29) 1.22 (1.13–1.32)
> 2–4 drink/day 205 (2.7) 169 (2.3) 0.89 (0.72–1.10) 0.95 (0.77–1.18)
> 4 drink/day 91 (1.2) 78 (1.0) 0.92 (0.68–1.25) 0.96 (0.70–1.31)
P for trenda 0.04 0.04
Total amount of lifetime drinking
Never 5005 (66.8) 4807 (64.1) 1 (reference) 1 (reference)
> 0–40 drink–years 764 (10.2) 748 (10.0) 1.04 (0.93–1.17) 1.08 (0.96–1.21)
> 40–60 drink–years 441 (5.9) 522 (7.0) 1.28 (1.11–1.48) 1.31 (1.14–1.51)
> 60–90 drink–years 866 (11.6) 958 (12.8) 1.21 (1.08–1.35) 1.21 (1.09–1.36)
> 90 drink–years 418 (5.6) 459 (6.1) 1.18 (1.02–1.37) 1.24 (1.07–1.44)
P for trenda < 0.01 < 0.01

OR odds ratio, CI confidence interval.

aTrend test was calculated for the associations between alcohol use patterns as a continuous variable and incident cataract surgery.

bConditional logistic regression matched for sex, age, admission date, and hospital.

cAdditionally adjusted for smoking history, lifestyle-related comorbidities (hypertension, hyperlipidaemia, diabetes, and obesity), occupational radiation exposure, and outdoor work.