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. 2022 Nov 22;8:124. doi: 10.1038/s41523-022-00491-1

Table 3.

AUCs of models for pCR prediction in the primary and validation cohorts.

CPTSM (95% CI) CPTILM (95% CI) CPM (95% CI)
PC 0.806 (0.78–0.83) 0.782 (0.73–0.83) 0.763 (0.72–0.81)
 p value1 <0.001 0.04 1
 p value2 0.005 1
VCs 0.788 (0.783–0.793) 0.762 (0.756–0.768) 0.747 (0.742–0.752)
 p value1 0.027 0.180 1
 p value2 0.078 1

p value refers to Delong test for the differences of AUCs between different metrics in different cohorts; p value1 refers the comparisons with the CPM while p value2 refers the comparisons with CPTILM.

AUC area under receiver operating characteristic curve, pCR pathological complete response, CPM clinicopathology-based model, CPTILM clinicopathology and sTILs based model, CPTSM clinicopathology and TS-score based model.