Table 3.
AUCs of models for pCR prediction in the primary and validation cohorts.
| CPTSM (95% CI) | CPTILM (95% CI) | CPM (95% CI) | |
|---|---|---|---|
| PC | 0.806 (0.78–0.83) | 0.782 (0.73–0.83) | 0.763 (0.72–0.81) |
| p value1 | <0.001 | 0.04 | 1 |
| p value2 | 0.005 | 1 | – |
| VCs | 0.788 (0.783–0.793) | 0.762 (0.756–0.768) | 0.747 (0.742–0.752) |
| p value1 | 0.027 | 0.180 | 1 |
| p value2 | 0.078 | 1 | – |
p value refers to Delong test for the differences of AUCs between different metrics in different cohorts; p value1 refers the comparisons with the CPM while p value2 refers the comparisons with CPTILM.
AUC area under receiver operating characteristic curve, pCR pathological complete response, CPM clinicopathology-based model, CPTILM clinicopathology and sTILs based model, CPTSM clinicopathology and TS-score based model.